巴西专利BR112013011658B1 online liquid drug medical device for use with a saline source and a medical container for reconstit

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专利摘要:
MEDICAL DEVICE FOR LIQUID DRUGS ONLINE WITH ROTARY FLOW CONTROL MEMBER. The present invention relates to in-line liquid drug medical devices for use with a physiological fluid source and a medical container for purposes of reconstitution and administration of the liquid drug. In-line liquid drug medical devices include a housing having a longitudinal device axis, a rotary flow control member and a bottle adapter for transposing the flow control member from a first initial flow control position for the purpose of reconstitution of the liquid drug to a second flow control position for purposes of liquid drug administration. Medical devices for online liquid drugs include a syringe port and a port for dispensing coaxial drug with the axis of the device. The rotary flow control member is rotatable on a coaxial rotation axis with the syringe port and the drug delivery port.
公开号:BR112013011658B1
申请号:R112013011658-7
申请日:2011-10-27
公开日:2020-12-08
发明作者:Igor Denenburg；Nimrod Lev；Moshe Gilboa
申请人:Medimop Medical Projects Ltd；
IPC主号:

专利说明:

Field of invention
[0001] The present invention relates to medical devices for online liquid drugs for purposes of reconstitution and administration of the liquid drug. Background of the invention
[0002] United States Patent 6,238,372 entitled "Fluid Control Device" illustrates and describes a fluid control device for use with a syringe and at least one medical container. The fluid control device includes a first port, a second port for receiving the syringe, a third port including an adapter having a member of the fluid channel that extends into the medical container when attached to it and a control member of flow selectively disposed of a first fluid control position that allows a flow passage between a first pair of two ports and a second flow control position allowing a flow passage between a second pair of two ports. The flow control member is coupled to one of the ports for manipulation between its fluid control positions.
[0003] PCT international application for common property PCT / IL2005 / 000376 entitled "Medical liquid drug devices" and published in PCT International Publication WO 2005/105014 illustrates and describes a liquid drug medical device for drug reconstitution and administration purposes liquid, a bottle adapter with elastomeric tubing and a needle guard removal device. The liquid drug medical device has a longitudinal axis and is intended for use with a saline source and a medical container. The liquid drug medical device includes a body member having a first port for fluid connection to the saline source and a flow control member pivotally mounted on the body member on a codirectional axis of rotation with the longitudinal axis. The flow control member has a first major flow duct and a second major flow duct substantially parallel and not coaxial with the axis of rotation and respectively ending at a second port, and a third port for administering the liquid drug. The liquid drug medical device further includes a manually rotating adapter having a fluid channel member with a close end in fluid communication with the second port and a distal end that extends to the medical container in its attachment to the adapter, and coupled to the member flow control to rotate between a first fluid control position to connect the first port to the second port, and a second flow control position to connect the first port to the third port.
[0004] The international PCT common application PCT / US2008 / 070024 entitled "Medicine mixing and injection apparatus" and published in PCT International Publication WO 2009/038860 illustrates and describes a mixing and injection apparatus including a needle and a needle base, a syringe fixing element and a mixing chamber engagement assembly including a needle chamber around the needle and a first part of the liquid channel, sealed from the needle chamber and a mixing chamber engagement part including a second part of the liquid channel that communicates with the first part of the liquid channel and configured for communication with a mixing chamber. The syringe clamp and the base needle are configured to allow liquid communication between an interior of the syringe and the first part of the liquid channel when the syringe clamp and the base needle are in the first relative engagement orientation and for allow liquid communication between an interior of the syringe and the needle when the syringe holding element and the base needle are in the second relative engagement orientation, axially separated from the first relative orientation by the injection axis.
[0005] The international application for common property PCT / IL2010 / 000915 entitled "Medical Liquid Drug Devices in line with displaceable sliding flow control member" and published in PCT International Publication No. WO2011 / 058548 illustrates and describes medical devices of in-line liquid drug having a longitudinal device axis, a housing with a linear displaceable sliding flow control member displaceable along a transverse bore of a first flow control position to establish flow communication between a first pair of ports for liquid drug reconstitution purposes between a second pair of ports for liquid drug delivery purposes, and a manually operated drive mechanism to apply a linear displacement force to stimulate the control flow member to slide through its first bore flow control position to your second flow control position. Summary of the invention
[0006] The present invention is directed to in-line liquid drug medical devices for use with a physiological fluid source and a medicinal container for purposes of reconstitution and administration of the liquid drug. The in-line liquid drug medical device includes a housing having a longitudinal device axis and a vial adapter removably attached to the housing and separated from it by a codirectional separation line with the device axis. The housing includes a port collector having a first port for fluid connection to a physiological fluid source and a drug dispenser port fitted with a drug dispenser such as a needle, an atomizer, and the like, for drug delivery purposes liquid. The first port and the drug delivery port are coaxial with the axis of the device to facilitate intuitive use of the device. The in-line liquid drug medical device further includes a rotary flow control member pivotally mounted on the door manifold on an axis of rotation coaxial with the axis of the device. The flow control member includes a second port for fluid communication with a medicinal container for purposes of reconstituting the liquid drug. The vial adapter is configured to extract from the housing to transpose a rotary flow control member from a first initial flow control position for liquid drug reconstitution purposes to a second subsequent flow control position for drug administration purposes liquid. Brief description of the drawings
[0007] To understand the invention and see how it can be carried out in practice, the preferred modalities will now be described, in the form of non-limiting examples only, with reference to the attached drawings in which similar parts are equally numbered, and in which :
[0008] Figure 1 is a pictorial representation of a syringe, a drug vial and a medical device for liquid drug in line having a housing, a rotary flow control member and a manually rotating vial adapter;
[0009] Figure 2 is a perspective view of the device of Figure 1;
[0010] Figure 3 is an enlarged view of the device of figure 1;
[0011] Figure 4A is a longitudinal cross-section of the device in Figure 1 along line AA in Figure 1 showing the flow control member in a first flow control position for purposes of reconstituting the liquid drug and the bottle adapter in an initial liquid drug reconstitution position;
[0012] Figure 4B is an enlarged cross-sectional view of the housing of figure 4A;
[0013] Figure 5A is a longitudinal cross-section of the device in Figure 1 along line A-A in Figure 1 showing its flow control member in a first fluid control position for purposes of reconstituting the liquid drug;
[0014] Figure 5B is an enlarged detailed cross-sectional view of the housing in figure 5A; and
[0015] Figure 6A to 6G shows the use of the device of figure 1 for purposes of reconstitution and administration of the liquid drug. Detailed description of the preferred embodiments of the invention
[0016] Figure 1 shows a syringe 10 which constitutes a source of physiological fluid, a vial 20 which constitutes a medicinal container and a medical device for in-line liquid drug 100 for use with syringe 10 and vial 20. Syringe 10 includes a barrel 11 with a plunger 12 and a male Luer lock connector 13. Syringe 10 can be formed with other types of connectors. The vial 20 includes a top open bottle 21 sealed by a vial cap 22 bounded by a metal strip 23 or other suitable limited material. Vial 20 contains a liquid or powder drug 24. Syringe 10 typically contains diluent to reconstitute contents of vial 24.
[0017] Figures 2 to 5B show the in-line liquid drug medical device 100 having an axis of the longitudinal device 101, and including a housing 102, a rotary flow control member 103, a manually rotating vial adapter 104 and a rigidly mounted tubular sleeve 106. Housing 102 includes a syringe port 107 which constitutes a first port coaxial with the axis of the device 101. Syringe port 107 is typically implemented as a female Luer connector for engaging the threaded thread with the male Luer lock 13. Housing 102 includes a conical port collector 108 integrally formed with the syringe port 107 and tapering from one end of the port collector close to the wide diameter 108A adjacent to the syringe port 107 toward an end of the collector of the distal threaded door 108B.
[0018] The port collector 108 includes a tapered peripheral surface 109 and a rim 111 circumferentially around the collector end of the nearby port 108A having two radially opposing fixing wings 111A. The port collector 108 includes a locking thread 112 at its end of the distal port collector 108B for engaging the thread between housing 102 and the bottle adapter 104. The end of the distal port collector 108B includes a recess in the port collector 113 to secure the flow control member 103 to it.
[0019] The port collector 108 includes a minor flow channel 114 transverse to the axis of the device 101 and extending radially from the syringe port 107 to the peripheral surface of the port collector 109. The port collector 108 includes a dispensing port drug 116 constituting a third coaxial port with the device axis 101 and the syringe port 107. The drug delivery port 116 extends during the process between the syringe port 107 and the distal end of the port 108B collector at the end distal of the 108B port collector. The drug delivery port 116 is preferably fitted with a drug delivery device in the form of a needle 117, a spray nozzle, and the like, for purposes of delivering the liquid drug. The port collector 108 includes a full hole 118 transverse to the axis of the device 101 and in fluid communication with the drug delivery port 116 so that they look like a T.
[0020] The flow control member 103 is is pivotally mounted on the port collector 108 on an axis of rotation 119 coaxial with the device axis 101, the syringe port 107 and the drug delivery port 116. The flow control 103 has a cylindrical outer wall 121 and a tapered inner wall 122 facing the port collector 108 to seal the assembly therein. The flow control member 103 includes an end close to the flow control member 103A and a distal end of the flow control member 103B. The flow control member 103 is shorter than the port collector 108 and is mounted thereon so that the distal end of the port collector 108B exits through the distal end of the flow control member 103B. The distal end of the flow control member 103B has a bottom face surface 123 formed with a cavity 124 and an opposite blind cavity 126.
[0021] The flow control member 103 includes an axially directed liquid drug reconstitution channel 127 having a close opening 128 and ending at a second distal port 129 consisting of cavity 124. The close opening 128 is in fluid communication with the channel minor flow 114 in a first flow control initial position of flow control member 103 to establish fluid communication between syringe port 107 and second port 129 (see figures 4A and 4B). Flow control member 103 includes an axial liquid drug delivery channel 131 formed on its own internal conical wall 122 in fluid communication with minor flow channel 114 when flow control member 103 is in a second control position flow flow to establish fluid communication between syringe port 107 and drug delivery port 116 (see figures 5A and 5B).
[0022] The bottle adapter 104 includes a skirt 132 with an upper surface 133 and down depending on the flexing members 134 to fit the drug bottle 20. The bottle adapter 104 includes an elongated vertical stem 136 having two stem walls curved opposites parallel 136A and 136B lateral to the axis of the device 101. The stem 136 includes ribs of the annular stem 137 in a direction transverse to the axis of the device 101. The ribs of the stem 137 are formed with complete openings 138 to receive the needle 117 coupling o vial adapter 104 in housing 102. The stem wall 136A ends at a stem tip connector 139A and the stem wall 136B ends at a stem tip connector 139B. Each stem wall 136 has an engagement tooth 141 for engaging the locking thread 112 to separately attach the adapter of the bottle 104 to the housing 102. The stem tip connectors 139A and 139B fit into the cavities 124 and 126 respectively to attach the adapter from flask 104 to flow control member 103 in the initial liquid drug reconstitution position of flask adapter 104 to allow flask adapter 104 to rotate flow control member 103 with respect to port 108 collector.
[0023] The stem wall 136A includes a fluid channel 142 codirectional with the axis of the device 101 and lateral to it. Fluid channel 142 has an end close to fluid channel 142A in stem tip connector 139A to seal the insert in second port 129. Fluid channel 142 has distal end 142B in fluid communication with a fluid interconnect channel radial 143. Fluid interconnect channel 143 is in fluid communication with a coaxial drilling cannula 144 to pierce the lids of the vial 22 in the insert assembly of the vial adapter 104 in the drug vial 20. The perforating cannula 144 extends so that by inverting drug vial 20 the entire liquid drug content can be aspirated from it through the perforation cannula 144.
[0024] In the first flow control position, the locking thread 112 is engaged by the locking tooth 141 to prevent the bottle adapter 104 from being separated from the housing 102. As the bottle adapter 104 is rotated to unscrew the tooth latch 141 of the fastening thread 112; the flask adapter 104 simultaneously rotates the flow control member 103 from its first flow control position to its second flow control position. The engagement tooth 141 disengages completely from the fastening thread 112 after transposing the flow control member 103 in its second flow control position, when the bottle adapter 104 is completely separated from the housing 102 by the codirectional separation line with the shaft device 101.
[0025] Glove 106 includes an end close to glove 106A with a pair of fixing notches 146 to attach to fixing wings 111A to secure glove 106 in housing 102 and a distal end of glove 106B terminating at the distal end of the collector of the port 108B. The sleeve 106 around the flow control member 103 to allow convenient user retention of the medical device of the online liquid drug 100.
[0026] Figures 6A to 6G show the use of the online liquid drug medical device 100 for purposes of reconstitution and administration of the liquid drug as follows:
[0027] Figure 6A shows the device 100 in its initial state ready for reconstitution of the liquid drug. The bottle adapter is screwed into the housing in its initial liquid drug reconstitution position and engages the flow control member in its first initial flow control position to protect fluid communication between the syringe port and the cannula. A user retains the glove and assembles the device 100 in a drug bottle 20, as indicated by the arrow M.
[0028] Figure 6B shows the user approaching syringe 10 towards device 100, as indicated by arrow N, and screwing syringe 10 onto device 100, as indicated by arrow O.
[0029] Figure 6C shown the user injecting the contents of the syringe into the drug bottle 20, as indicated by the arrow P. The user shakes the assembly to reconstitute the liquid drug.
[0030] Figure 6D shows the user inverting the assembly and aspirating the reconstituted contents of the liquid drug in syringe 10, as indicated by arrow Q.
[0031] Figure 6E shows the user rotating the bottle adapter with respect to the housing as indicated by the arrow S to simultaneously transpose the flow control member into its second subsequent flow control position and separate the bottle adapter from the housing as indicated by the arrow S (see figure 6F). In this position, the syringe port is in fluid communication with the drug delivery port and the needle is exposed for administration purposes (see figure 6G).
[0032] While the invention has been described with respect to a limited number of modalities, it will be appreciated that many variations, modifications, and other applications of the invention can be made within the scope of the appended claims. For example, the stem may include a solid part with a fluid channel and a blind needle hole.

权利要求:
Claims (3)
[0001]
1. In-line liquid drug medical device (100) for use with a saline source and a medicinal container for reconstitution and administration of a liquid drug, the in-line liquid drug medical device having a longitudinal device axis (101) , and comprising: (a) a housing (102) including a first port (107) for fluid connection to the source of saline, and an integrally formed port collector (108) having a peripheral port collector surface (109) and a smaller flow duct (114) transversal to the axis of the device (101) and extending said first door (107) radially to said surface of the peripheral door collector (109), said first door (107) being coaxial with the device axis (101); (b) a revolving flow control member (103) having a second port (129) and revolving in said port collector (108) on a rotation axis (119) coaxial with the device axis (101), and the said first port (107) of a first initial flow control position in which the smaller flow duct (114) is in fluid communication with the second port (129) to establish fluid communication between said first port (107) and the said second port (129) for purposes of reconstituting the liquid drug in a second subsequent flow control position to establish fluid communication between said first port (107) and the port for dispensing drug (116) for purposes of liquid drug delivery ; and (c) a manually rotating vial adapter (104) to fit the medical container (20) and including an elongated vertical rod (136) for initial engagement with said flow control member (103) in said first control position flow rate in an initial liquid drug reconstitution position of said vial adapter, said vial adapter (104) having a fluid channel (142) co-directional to the axis of the device (101) and lateral to it, said channel of the fluid (142) having a near end (142A) in fluid communication with said second port (129) and a distal end (142B) in fluid communication with a puncture cannula (144) which extends in the medical container in the fixation of the said vial adapter (104) in said initial liquid drug reconstitution position, said vial adapter (104) being manually pivoted from said housing (102) by the codirectional separation line with the device axis (101) to simulate simultaneously transposing said flow control member (103) from said first initial flow control position to said second subsequent flow control position, characterized by the fact that the port collector (108) includes the port for dispensing drugs ( 116), said drug delivery port (116) being coaxial to said first port (107) and the device axis (101), and said flow control member (103) having an internal wall (122) facing the said port collector (108) and having an axial liquid drug delivery channel (131) in fluid communication with said minor flow duct (114) in said second flow control position to allow fluid communication between said first door (107) and said door for dispensing drug (116) from the door collector (108).
[0002]
2. Device according to claim 1, characterized in that said vertical elongated stem (136) includes two opposing spaced apart stem walls (136A, 136B) separated at least by a transverse stem rib (137), wherein a stem wall includes said fluid channel (142) and an arrangement (138) for receiving a needle (117) disposed in said drug delivery port (116).
[0003]
Device according to claim 1 or 2, characterized by the fact that said housing (102) still includes a fixedly mounted sleeve (106) that surrounds said flow control member (103) to assist a user in operating the device allowing the user to hold said glove (106) in one hand and rotate said bottle adapter (104) with respect to said housing (102) with his other hand.

类似技术:

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引用文献:

公开号 | 申请日 | 公开日 | 申请人 | 专利标题

US62333A|1867-02-26|Henry holl |

US1021681A|1911-02-13|1912-03-26|John F Jennings|Valve for corrosive liquids.|

US1704817A|1928-01-17|1929-03-12|Okadee Company|Locomotive-cylinder cock|

US1930944A|1932-12-21|1933-10-17|Jr William L Schmitz|Measuring dispenser|

US2326490A|1942-06-13|1943-08-10|Harold N Perelson|Fluid dispenser|

US3059643A|1954-12-10|1962-10-23|Baxter Laboratories Inc|Pumping apparatus|

US2931668A|1956-04-30|1960-04-05|Bastian Blessing Co|Coupling|

US2968497A|1958-02-05|1961-01-17|Avro Aircraft Ltd|Self-sealing coupling|

DE1945279U|1966-07-02|1966-09-01|Gruenenthal Chemie|AUXILIARY DEVICE FOR THE PRODUCTION OF STERILE SOLUTIONS.|

FR2029242A5|1969-01-21|1970-10-16|Alriq Christian|Self-perforable plug for bacteriological - culture tubes|

DE1913926A1|1969-03-19|1970-09-24|Hoechst Ag|Two-chamber syringe|

US3757981A|1969-11-24|1973-09-11|Harris R|Valves and valve needle syringes|

US3618637A|1970-02-04|1971-11-09|Deseret Pharma|Rotary mixing valve|

US3788524A|1971-12-22|1974-01-29|Cutter Lab|Additive container|

US3826261A|1971-12-27|1974-07-30|Upjohn Co|Vial and syringe assembly|

US3822700A|1973-03-16|1974-07-09|M Pennington|Intravenous solution dispenser|

US4109670A|1973-05-16|1978-08-29|Slagel Roger D|Combination check flow control and selector valve|

US3872992A|1973-08-06|1975-03-25|Pharmaco Inc|Medicament vial stopper piercing and needle positioning device|

US3885607A|1973-11-16|1975-05-27|Richard I Peltier|Device for providing fluid communication between two sealed vessels|

FR2268707B1|1974-04-26|1976-12-17|Becton Dickinson France|

US3977555A|1974-05-07|1976-08-31|Pharmaco, Inc.|Protective safety cap for medicament vial|

US3938520A|1974-06-10|1976-02-17|Abbott Laboratories|Transfer unit having a dual channel transfer member|

US3957052A|1974-09-13|1976-05-18|Medical Development Corporation|Pumping-syringe|

US3993063A|1975-06-16|1976-11-23|Union Carbide Corporation|Protective shielding assembly for use in loading a hypodermic syringe with radioactive material|

US4051852A|1975-06-26|1977-10-04|The Kendall Company|Aspirating device|

US4020839A|1976-02-26|1977-05-03|Parke, Davis & Company|Medicament-dispensing package|

US4210173A|1976-12-06|1980-07-01|American Hospital Supply Corporation|Syringe pumping system with valves|

US4121585A|1977-01-24|1978-10-24|Becker Jr Karl E|Anti backflow injection device|

DE2714094C3|1977-03-30|1980-04-17|Bayer Ag, 5090 Leverkusen|Device for determining the water content of isotropic materials with the aid of microwave absorption|

US4187848A|1977-07-18|1980-02-12|The Kendall Company|Adapter assembly|

US4203443A|1977-12-08|1980-05-20|Abbott Laboratories|Additive transfer unit with interlocking means|

US4161178A|1977-12-08|1979-07-17|Abbott Laboratories|Additive transfer device|

US4314586A|1978-08-30|1982-02-09|Tronomed International, Inc.|Disposable valve|

US4639019A|1979-06-04|1987-01-27|Baxter Travenol Laboratories, Inc.|Luer connection|

US4312349A|1979-07-23|1982-01-26|Cohen Milton J|Filter device for injectable fluid|

US4296786A|1979-09-28|1981-10-27|The West Company|Transfer device for use in mixing a primary solution and a secondary or additive substance|

US4253501A|1979-11-09|1981-03-03|Ims Limited|Transfer system|

US4303067A|1980-01-21|1981-12-01|American Hospital Supply Corporation|Medical liquid bag having an improved additive port|

US4328802A|1980-05-14|1982-05-11|Survival Technology, Inc.|Wet dry syringe package|

US4376634A|1980-05-30|1983-03-15|Mallinckrodt, Inc.|Assay kit having syringe, dilution device and reagents within sealed container|

US4335717A|1980-10-10|1982-06-22|Abbott Laboratories|I.V. Administration set with retrograde volume|

US4434823A|1981-06-29|1984-03-06|American Hospital Supply Corporation|Liquid transfer device|

US4493348A|1981-06-29|1985-01-15|Pur/Acc Corporation|Method and apparatus for orally dispensing liquid medication|

US4465471A|1981-08-26|1984-08-14|Eli Lilly And Company|Intravenous administration system for dry medicine|

US4392850A|1981-11-23|1983-07-12|Abbott Laboratories|In-line transfer unit|

US4458733A|1982-04-06|1984-07-10|Baxter Travenol Laboratories, Inc.|Mixing apparatus|

US4410321A|1982-04-06|1983-10-18|Baxter Travenol Laboratories, Inc.|Closed drug delivery system|

US4475915A|1982-05-07|1984-10-09|Sloane Glenn L|Holder for a syringe and an ampoule|

US4588396A|1982-10-22|1986-05-13|Stroebel Maurice G|Apparatus for gravity feed of liquid under constant hydrostatic pressure|

US4507113A|1982-11-22|1985-03-26|Derata Corporation|Hypodermic jet injector|

US4752292A|1983-01-24|1988-06-21|Icu Medical, Inc.|Medical connector|

US5688254A|1983-01-24|1997-11-18|Icu Medical, Inc.|Medical connector|

US4505709A|1983-02-22|1985-03-19|Froning Edward C|Liquid transfer device|

US4676530A|1983-04-07|1987-06-30|Warner-Lambert Company|Coupling assembly for use in fluid flow systems|

US4778447A|1983-05-20|1988-10-18|Travenol European Research & Development Center|Connectors|

EP0126718A3|1983-05-20|1985-10-23|Bengt Gustavsson|A device for transferring a substance from one vessel to another and further to the intended application|

JPS6026391U|1983-07-30|1985-02-22|

US4532969A|1983-09-21|1985-08-06|Kwaan Hau C|Fluid withdrawal and instillation device|

US4573993A|1983-09-29|1986-03-04|Instafil, Inc.|Fluid transfer apparatus|

US4743243A|1984-01-03|1988-05-10|Vaillancourt Vincent L|Needle with vent filter assembly|

IT1173370B|1984-02-24|1987-06-24|Erba Farmitalia|SAFETY DEVICE TO CONNECT A SYRINGE TO THE MOUTH OF A BOTTLE CONTAINING A DRUG OR A TUBE FOR DISPENSING THE SYRINGE DRUG|

US4581014A|1984-04-03|1986-04-08|Ivac Corporation|Fluid infusion system|

US5088996A|1984-04-16|1992-02-18|Kopfer Rudolph J|Anti-aerosoling drug reconstitution device|

US4697622A|1984-06-01|1987-10-06|Parker Hannifin Corporation|Passive filling device|

US4588403A|1984-06-01|1986-05-13|American Hospital Supply Corporation|Vented syringe adapter assembly|

US4604093A|1984-06-12|1986-08-05|I-Flow Corporation|Apparatus and method for administering multiple fluid infusions|

US5113904A|1984-07-13|1992-05-19|Aslanian Jerry L|Flow control device for administration of intravenous fluids|

US4607671A|1984-08-21|1986-08-26|Baxter Travenol Laboratories, Inc.|Reconstitution device|

JPH0362426B2|1984-09-10|1991-09-25|Terumo Corp|

US4759756A|1984-09-14|1988-07-26|Baxter Travenol Laboratories, Inc.|Reconstitution device|

US4614437A|1984-11-02|1986-09-30|Dougherty Brothers Company|Mixing container and adapter|

US4721133A|1985-09-26|1988-01-26|Alcon Laboratories, Inc.|Multiple use valving device|

US4667927A|1985-11-08|1987-05-26|Rao Medical Devices, Inc.|Liquid flow metering device|

US4865592A|1986-02-20|1989-09-12|Becton, Dickinson And Company|Container and needle assembly|

US4834152A|1986-02-27|1989-05-30|Intelligent Medicine, Inc.|Storage receptacle sealing and transfer apparatus|

US4735608A|1986-05-14|1988-04-05|Del F. Kahan|Apparatus for storing and reconstituting antibiotics with intravenous fluids|

US5049129A|1986-05-29|1991-09-17|Zdeb Brian D|Adapter for passive drug delivery system|

SE461765B|1986-07-10|1990-03-26|Haessle Ab|DEVICE FOR RELEASE OF SUBSTANCE|

IT1201801B|1986-08-04|1989-02-02|Pietro Cosmai|MIXER LOADER FOR TRANSCUTANEOUS INJECTORS|

US4743229A|1986-09-29|1988-05-10|Collagen Corporation|Collagen/mineral mixing device and method|

US4683975A|1986-09-30|1987-08-04|General Motors Corporation|Vehicle power window control|

US4797898A|1986-11-21|1989-01-10|Racal Data Communications Inc.|Method and apparatus for equalization of data transmission system|

US4832690A|1987-01-23|1989-05-23|Baxter International Inc.|Needle-pierceable cartridge for drug delivery|

US4729401A|1987-01-29|1988-03-08|Burron Medical Inc.|Aspiration assembly having dual co-axial check valves|

US5041105A|1987-03-03|1991-08-20|Sherwood Medical Company|Vented spike connection component|

US4787898A|1987-05-12|1988-11-29|Burron Medical Inc.|Vented needle with sideport|

US4758235A|1987-05-26|1988-07-19|Tu Ho C|Cardiopulmonary resuscitation medication assembly|

AU101237S|1987-06-18|1988-09-08|Ab Astra|Transfer cannula|

US5178607A|1987-07-31|1993-01-12|Lynn Lawrence A|Blood aspiration assembly septum and blunt needle aspirator|

IT211830Z2|1987-09-22|1989-05-25|Farmitalia Carl Erba S P A|SAFETY DEVICE FOR THE INTRODUCTION AND WITHDRAWAL OF LIQUIDS IN AND FROM DRUG BOTTLES AND SIMILAR.|

US4804366A|1987-10-29|1989-02-14|Baxter International Inc.|Cartridge and adapter for introducing a beneficial agent into an intravenous delivery system|

US5211638A|1988-01-25|1993-05-18|Baxter International Inc.|Pre-slit injection site|

DE3804429A1|1988-02-12|1989-08-24|Schleicher & Schuell Gmbh|DISPOSABLE FILTER|

US4932944A|1988-03-09|1990-06-12|The University Of Virginia Alumni Patents Foundation|Intravenous port injection and connector system|

US4857062A|1988-03-09|1989-08-15|Medical Parameters, Inc.|Catheter introducer valve|

US4931040A|1988-04-13|1990-06-05|Habley Medical Technology|Safety syringe having a combination needle cannula and articulating hub for retracting said cannula into a medication carpule|

US4898209A|1988-09-27|1990-02-06|Baxter International Inc.|Sliding reconstitution device with seal|

US5122124A|1988-12-14|1992-06-16|Patco Ventures Ltd.|Safety syringe needle device with interchangeable and retractable needle platform|

US6344031B1|1989-03-22|2002-02-05|Laurel A. Novacek|Safety syringe needle device with interchangeable and retractable needle platform|

US5301685A|1989-01-10|1994-04-12|Guirguis Raouf A|Method and apparatus for obtaining a cytology monolayer|

US5035686A|1989-01-27|1991-07-30|C. R. Bard, Inc.|Catheter exchange system with detachable luer fitting|

US5135492A|1989-06-26|1992-08-04|University Of Florida|Arterial/venous fluid transfer system|

US4967797A|1989-08-16|1990-11-06|Manska Wayne E|Tap valve|

US5053015A|1989-08-30|1991-10-01|The Kendall Company|Locking catheter adapter|

US4997430A|1989-09-06|1991-03-05|Npbi Nederlands Produktielaboratorium Voor Bloedtransfusieapparatuur En Infusievloeistoffen B.V.|Method of and apparatus for administering medicament to a patient|

US5578015A|1989-09-18|1996-11-26|Robb Pascal Patent Limited|Safety syringe incorporating automatic needle holder release|

US5304163A|1990-01-29|1994-04-19|Baxter International Inc.|Integral reconstitution device|

US5125915A|1990-03-02|1992-06-30|Cardiopulmonics, Inc.|Locking y-connector for selective attachment to exterior of medical tubing|

US5061248A|1990-04-04|1991-10-29|Sacco John J|Injection port safety shield|

US5006114A|1990-04-20|1991-04-09|Rogers Bobby E|Medical valve assembly|

US5104387A|1990-05-25|1992-04-14|St. Jude Medical, Inc.|Bi-planar fluid control valve|

US5045066A|1990-06-07|1991-09-03|Smith & Nephew, Inc.|Dental needle with stick resistant protective sleeve|

US5203775A|1990-09-18|1993-04-20|Medex, Inc.|Needleless connector sample site|

US5125908A|1990-10-19|1992-06-30|Cohen Milton J|Hypodermic syringe with protective holder|

US5201717A|1990-12-05|1993-04-13|Philip Wyatt|Safety enclosure|

US5232029A|1990-12-06|1993-08-03|Abbott Laboratories|Additive device for vial|

US5607439A|1993-06-24|1997-03-04|Yoon; Inbae|Safety penetrating instrument with penetrating member moving during penetration and triggered safety member protrusion|

JP3066611B2|1991-04-30|2000-07-17|武田薬品工業株式会社|Aseptic holding and mixing device for two drugs housed in individually sealed containers|

US5183469A|1991-05-10|1993-02-02|Becton, Dickinson And Company|Device for the removal and replacement of a needle shield|

DE4122221A1|1991-07-04|1993-03-18|Axel Von Brand|TRANSFER AND REMOVAL SPIKE|

DE4122476A1|1991-07-06|1993-01-07|Leopold Pharma Gmbh|Sterile liq. transfer in e.g. medical infusion mixts. - using double, self sealing, spined cannula coupling|

US5288290A|1991-09-25|1994-02-22|Alcon Surgical, Inc.|Multi-ported valve assembly|

US5242432A|1991-09-26|1993-09-07|Ivac|Needleless adapter|

WO1993010001A1|1991-11-21|1993-05-27|Gds Technology, Inc.|Fluid transfer device|

US5171230A|1991-11-29|1992-12-15|Medex, Inc.|Fast flush catheter valve|

US5247972A|1991-12-17|1993-09-28|Whittier Medical, Inc.|Alignment guide for hypodermic syringe|

CA2588574A1|1991-12-18|1993-06-24|Icu Medical, Inc.|Medical valve|

US5279597A|1992-01-13|1994-01-18|Arrow International Investment Corp.|Catheter compression clamp|

CA2093560C|1992-04-10|2005-06-07|Minoru Honda|Fluid container|

US5328474A|1992-04-13|1994-07-12|B. Braun Medical Inc.|Tamper resistant syringe cap|

JP2605345Y2|1992-05-01|2000-07-10|株式会社大塚製薬工場|Drug container|

US5279576A|1992-05-26|1994-01-18|George Loo|Medication vial adapter|

US5232109A|1992-06-02|1993-08-03|Sterling Winthrop Inc.|Double-seal stopper for parenteral bottle|

GB9211912D0|1992-06-04|1992-07-15|Drg Flexpak Ltd|Vial connector system|

US5300034A|1992-07-29|1994-04-05|Minnesota Mining And Manufacturing Company|Iv injection site for the reception of a blunt cannula|

AU4999793A|1992-08-07|1994-03-03|West Company, Incorporated, The|Needleless access stopper|

US5308483A|1992-08-27|1994-05-03|Gelman Sciences Inc.|Microporous filtration funnel assembly|

US5344417A|1992-09-11|1994-09-06|Becton, Dickinson And Company|Universal fitting for inoculation receptacles|

US5334163A|1992-09-16|1994-08-02|Sinnett Kevin B|Apparatus for preparing and administering a dose of a fluid mixture for injection into body tissue|

US5603706A|1992-09-29|1997-02-18|Wyatt; Philip|Infusion apparatus|

US5334179A|1992-10-16|1994-08-02|Abbott Laboratories|Latching piercing pin for use with fluid vials of varying sizes|

US5547471A|1992-11-19|1996-08-20|Baxter International Inc.|In-line drug delivery device for use with a standard IV administration set and a method for delivery|

US5385547A|1992-11-19|1995-01-31|Baxter International Inc.|Adaptor for drug delivery|

DE69317650T2|1992-12-15|1998-10-08|Sanofi Sa|DEVICE FOR PREPARING A SOLUTION, SUSPENSION OR EMULSION OF A MEDICAL SOLUTION|

JP2604240Y2|1992-12-25|2000-04-24|川澄化学工業株式会社|Medical equipment|

US5405333A|1992-12-28|1995-04-11|Richmond; Frank M.|Liquid medicament bag with needleless connector fitting using boat assembly|

US5269768A|1993-02-08|1993-12-14|Smiths Industries Medical Systems, Inc.|Valved suction catheter|

US5766211A|1993-02-08|1998-06-16|Wood; Jan|Medical device for allowing insertion and drainage into a body cavity|

US5464111A|1993-03-03|1995-11-07|Sterling Winthrop|Closure for medication container|

US5312377A|1993-03-29|1994-05-17|Dalton Michael J|Tapered luer connector|

US5591143A|1993-04-02|1997-01-07|Medrad Inc.|Luer connector with torque indicator|

US5364386A|1993-05-05|1994-11-15|Hikari Seiyaku Kabushiki Kaisha|Infusion unit|

CN1106189C|1993-09-07|2003-04-23|生物技术公司|Syringe device for mixing two compounds|

CA2124970A1|1993-06-29|1994-12-30|R. Hayes Helgren|Pointed adapter for blunt entry device|

US5429614A|1993-06-30|1995-07-04|Baxter International Inc.|Drug delivery system|

US5445630A|1993-07-28|1995-08-29|Richmond; Frank M.|Spike with luer fitting|

US5364387A|1993-08-02|1994-11-15|Becton, Dickinson And Company|Drug access assembly for vials and ampules|

US5397303A|1993-08-06|1995-03-14|River Medical, Inc.|Liquid delivery device having a vial attachment or adapter incorporated therein|

US5451374A|1993-08-23|1995-09-19|Incutech, Inc.|Medicine vessel stopper|

US6146362A|1993-08-27|2000-11-14|Baton Development, Inc.|Needleless IV medical delivery system|

SE9303178D0|1993-09-29|1993-09-29|Kabi Pharmacia Ab|Improvements in injection cartridges|

US5509433A|1993-10-13|1996-04-23|Paradis; Joseph R.|Control of fluid flow|

US5699821A|1993-10-13|1997-12-23|Paradis; Joseph R.|Control of fluid flow|

US5806831A|1993-10-13|1998-09-15|Paradis; Joseph R.|Control of fluid flow with internal cannula|

US5472022A|1993-11-02|1995-12-05|Genentech, Inc.|Injection pen solution transfer apparatus and method|

US5549577A|1993-12-29|1996-08-27|Ivac Corporation|Needleless connector|

US5466220A|1994-03-08|1995-11-14|Bioject, Inc.|Drug vial mixing and transfer device|

US5554128A|1994-03-09|1996-09-10|Joseph K. Andonian|Syringe and vial connector|

US5520659A|1994-03-09|1996-05-28|Joseph K. Andonian|Syringe needle cover and vial connector|

US5454805A|1994-03-14|1995-10-03|Brony; Seth K.|Medicine vial link for needleless syringes|

US5462317A|1994-03-23|1995-10-31|Keller; Wilhelm A.|Adapter for a mixing or dispensing device|

US5527306A|1994-04-18|1996-06-18|Haining; Michael L.|Vial adapter|

DE4414697C2|1994-04-27|1998-06-18|Caremed Vertriebsgesellschaft|Device for transferring and removing liquids from bottles, bags or similar containers for medical purposes|

US5746733A|1994-05-19|1998-05-05|Becton, Dickinson And Company|Syringe filling and delivery device|

US5832971A|1994-05-19|1998-11-10|Becton, Dickinson And Company|Syringe filling and delivery device|

AT168554T|1994-05-23|1998-08-15|Liposome Co Inc|DEVICE FOR PRODUCING A FORMULATION|

US5649637A|1994-06-02|1997-07-22|Automatic Liquid Packaging, Inc.|Torque-resistant closure for a hermetically sealed container|

JP3456019B2|1994-06-17|2003-10-14|ニプロ株式会社|Liquid introduction needle and aid for dissolving dry preparation using the same|

US6183448B1|1994-06-20|2001-02-06|Bruno Franz P. Mayer|Needleless injection site|

US5470319A|1994-06-20|1995-11-28|Critical Device Corporation|Needleless injection site|

EP1181921A3|1994-06-24|2002-03-06|ICU Medical, Inc.|Fluid transfer device and method of use|

EP0692235A1|1994-07-14|1996-01-17|International Medication Systems Ltd.|Mixing & dispensing apparatus|

US5526853A|1994-08-17|1996-06-18|Mcgaw, Inc.|Pressure-activated medication transfer system|

FR2726768A1|1994-11-14|1996-05-15|Debiotech Sa|SYRINGE DEVICE ATTACHABLE TO A VIAL|

US6681810B2|1994-12-20|2004-01-27|Aradigm Corporation|Filling device for a needleless injector cartridge|

GB9425642D0|1994-12-20|1995-02-22|Weston Medical Ltd|Filling device|

US5531695A|1994-12-22|1996-07-02|Sherwood Medical Company|Tamper evident sleeve|

US5616136A|1995-01-09|1997-04-01|Med-Safe Systems, Inc.|Quick release needle removal apparatus|

US5653686A|1995-01-13|1997-08-05|Coulter Corporation|Closed vial transfer method and system|

US5492147A|1995-01-17|1996-02-20|Aeroquip Corporation|Dry break coupling|

US5647845A|1995-02-01|1997-07-15|Habley Medical Technology Corporation|Generic intravenous infusion system|

US5674195A|1995-02-06|1997-10-07|Truthan; Charles Edwin|Syringe apparatus and method of mixing liquid medicants within a syringe|

DE19504413A1|1995-02-10|1996-08-22|Pharmacia Gmbh|Transfer device|

DE19506163C2|1995-02-22|1998-01-29|Hans Mueller|Blood treatment device|

US5584819A|1995-03-13|1996-12-17|Kopfer; Rudolph J.|Nested blunt/sharp injection assembly|

IL114960D0|1995-03-20|1995-12-08|Medimop Medical Projects Ltd|Flow control device|

US5651776A|1995-03-22|1997-07-29|Angiodynamics, Inc.|Luer-type connector|

AT181909T|1995-04-04|1999-07-15|Kuraray Co|METHOD FOR PRODUCING 6-METHYLHEPTAN-2-ON|

US5566729A|1995-04-06|1996-10-22|Abbott Laboratories|Drug reconstitution and administration system|

DE19513666C1|1995-04-11|1996-11-28|Behringwerke Ag|Device for bringing together a first liquid and a second solid or liquid component by means of negative pressure under sterile conditions|

US5902280A|1995-04-13|1999-05-11|Advanced Cytometrix, Inc.|Aspiration needle apparatus incorporating its own vacuum and method and adapter for use therewith|

SE509950C2|1995-05-02|1999-03-29|Carmel Pharma Ab|Device for the administration of toxic liquid|

US5839715A|1995-05-16|1998-11-24|Alaris Medical Systems, Inc.|Medical adapter having needleless valve and sharpened cannula|

NZ286445A|1995-05-16|1997-12-19|Ivac Corp|Needleless luer connector: deformable piston occludes bore|

US5685845A|1995-07-11|1997-11-11|Becton, Dickinson And Company|Sterile resealable vial connector assembly|

US5616203A|1995-07-14|1997-04-01|Merit Medical|Method of manufacturing a split ring airless rotatable connector|

FR2738550B1|1995-09-11|1997-11-07|Biodome|DEVICE FOR SEALING A CONTAINER ITSELF CLOSED, ASSEMBLY FOR PROVIDING A PRODUCT COMPRISING SUCH A CONTAINER AND SUCH A SEALING DEVICE|

US5702019A|1995-09-27|1997-12-30|Becton Dickinson France S.A.|Vial having resealable membrane assembly activated by a medical delivery device|

CA2185494A1|1995-09-27|1997-03-28|Jean-Pierre Grimard|Resealable vial with connector assembly having a membrane and pusher|

DE59610206D1|1995-10-20|2003-04-10|Schering Ag|ADAPTER FOR REMOVING A LIQUID FROM A CONTAINER CLOSED WITH A STOPPER|

US5611576A|1995-11-24|1997-03-18|Industrie Borla Spa|Female coupling element for haemodialysis medical equipment|

US5833213A|1995-12-29|1998-11-10|Rymed Technologies, Inc.|Multiple dose drug vial adapter for use with a vial having a pierceable septum and a needleless syringe|

ES2176661T3|1996-01-11|2002-12-01|Duoject Inc|SUPPLY SYSTEM FOR PHARMACEUTICAL PRODUCTS PACKAGED IN VIALESPHARMACEUTICALS.|

US5893397A|1996-01-12|1999-04-13|Bioject Inc.|Medication vial/syringe liquid-transfer apparatus|

US6629959B2|1996-02-27|2003-10-07|Injectimed, Inc.|Needle tip guard for percutaneous entry needles|

US5810792A|1996-04-03|1998-09-22|Icu Medical, Inc.|Locking blunt cannula|

WO1997039720A1|1996-04-22|1997-10-30|Abbott Laboratories|Container closure system|

GB9609563D0|1996-05-08|1996-07-10|Sterimatic Holdings Ltd|Venting devices|

DE19619026A1|1996-05-10|1997-11-13|Trinova Gmbh|Quick coupling|

US5897526A|1996-06-26|1999-04-27|Vaillancourt; Vincent L.|Closed system medication administering system|

US6296621B1|1996-08-23|2001-10-02|Baxter International Inc.|Receptacle for passive drug delivery|

US5871110A|1996-09-13|1999-02-16|Grimard; Jean-Pierre|Transfer assembly for a medicament container having a splashless valve|

CA2211629A1|1996-09-17|1998-03-17|Bernard Sams|Vial connector assembly for a medicament container|

US5873872A|1996-09-17|1999-02-23|Becton Dickinson And Company|Multipositional resealable vial connector assembly for efficient transfer of liquid|

FR2753624B1|1996-09-25|1999-04-16|Biodome|CONNECTION DEVICE, PARTICULARLY BETWEEN A CONTAINER WITH PERFORABLE CAP AND A SYRINGE|

US5738144A|1996-10-11|1998-04-14|Aeroquip Corporation|Luer connecting coupling|

US5817082A|1996-11-08|1998-10-06|Bracco Diagnostics Inc.|Medicament container closure with integral spike access means|

US5895383A|1996-11-08|1999-04-20|Bracco Diagnostics Inc.|Medicament container closure with recessed integral spike access means|

US5941848A|1996-11-14|1999-08-24|Baxter International Inc.|Passive drug delivery apparatus|

US6883778B1|1996-11-18|2005-04-26|Nypro Inc.|Apparatus for reducing fluid drawback through a medical valve|

JP3752631B2|1996-11-18|2006-03-08|ナイプロ・インク|Swabable lure cone valve|

US6004278A|1996-12-05|1999-12-21|Mdc Investment Holdings, Inc.|Fluid collection device with retractable needle|

FR2756811B1|1996-12-06|1999-02-05|Valois|DEVICE FOR DISPENSING BICOMPONENT TYPE FLUID PRODUCT|

GB9700177D0|1997-01-07|1997-02-26|Nycomed Imaging As|Container|

GB9701413D0|1997-01-24|1997-03-12|Smithkline Beecham Biolog|Novel device|

US5879337A|1997-02-27|1999-03-09|Injectimed, Inc.|Needle tip guard for hypodermic needles|

US5891129A|1997-02-28|1999-04-06|Abbott Laboratories|Container cap assembly having an enclosed penetrator|

US5924584A|1997-02-28|1999-07-20|Abbott Laboratories|Container closure with a frangible seal and a connector for a fluid transfer device|

US5911710A|1997-05-02|1999-06-15|Schneider/Namic|Medical insertion device with hemostatic valve|

US5772652A|1997-05-14|1998-06-30|Comar, Inc.|Stab cap for a vial having a puncturable seal|

US6042433A|1997-05-29|2000-03-28|The Whitaker Corporation|Electrical contact|

IT1293856B1|1997-06-27|1999-03-10|Borla Ind|TRANSDUCER-PROTECTOR DEVICE FOR BIOMEDICAL HEMODIALYSIS LINES|

US5755696A|1997-06-30|1998-05-26|Becton, Dickinson And Company|Syringe filling and delivery device|

US5899468A|1997-07-02|1999-05-04|Rehrig Pacific Company|Organic waste cart with vented lid|

US5820621A|1997-07-29|1998-10-13|Becton, Dickinson And Company|Medical fluid transfer and delivery device|

US7125397B2|1997-08-20|2006-10-24|B. Braun Melsungen Ag|Protective device for an injection needle|

IL121605A|1997-08-22|2001-03-19|Medimop Medical Projects Ltd|Fluid access assembly and a method for preparing a liquid drug|

US5834744A|1997-09-08|1998-11-10|The Rubbright Group|Tubular microwave applicator|

US5919182A|1997-09-12|1999-07-06|Becton, Dickinson And Company|Medical fluid transfer and delivery device|

US6036171A|1997-09-17|2000-03-14|Halkey-Roberts Corporation|Swabbable valve assembly|

US6090093A|1997-09-25|2000-07-18|Becton Dickinson And Company|Connector assembly for a vial having a flexible collar|

US5925029A|1997-09-25|1999-07-20|Becton, Dickinson And Company|Method and apparatus for fixing a connector assembly onto a vial with a crimp cap|

US5944700A|1997-09-26|1999-08-31|Becton, Dickinson And Company|Adjustable injection length pen needle|

US5935112A|1997-10-15|1999-08-10|Stevens; Brian W.|Hemostasis valve with catheter/guidewire seals|

US5902298A|1997-11-07|1999-05-11|Bracco Research Usa|Medicament container stopper with integral spike access means|

IT236233Y1|1997-11-26|2000-08-08|Eurospital S P A|DEVICE FOR THE CONNECTION OF A PHARMACEUTICAL PRODUCT CONTAINER TO A BAG OF LIQUID PRODUCT TO CARRY OUT THE|

US6090092A|1997-12-04|2000-07-18|Baxter International Inc.|Sliding reconstitution device with seal|

US6457488B2|1998-01-08|2002-10-01|George Loo|Stopcock having axial port for syringe twist actuation|

US6179822B1|1998-01-20|2001-01-30|Bracco Research Usa|Single use universal access device/medical container assembly|

US6179823B1|1998-01-20|2001-01-30|Bracco Research Usa|Multiple use universal connector flexible medical container assembly|

FR2773735B1|1998-01-20|2000-02-25|Becton Dickinson France|WATERPROOF CONTAINMENT DEVICE|

US6096011A|1998-01-29|2000-08-01|Medrad, Inc.|Aseptic connector and fluid delivery system using such an aseptic connector|

US6681946B1|1998-02-26|2004-01-27|Becton, Dickinson And Company|Resealable medical transfer set|

US6003566A|1998-02-26|1999-12-21|Becton Dickinson And Company|Vial transferset and method|

US6080132A|1998-02-27|2000-06-27|Abbott Laboratories|Apparatus for altering characteristics of a fluid|

US6221065B1|1998-04-03|2001-04-24|Filtertek Inc.|Self-priming needle-free “Y”-adapter|

US6209738B1|1998-04-20|2001-04-03|Becton, Dickinson And Company|Transfer set for vials and medical containers|

US6957745B2|1998-04-20|2005-10-25|Becton, Dickinson And Company|Transfer set|

US6378714B1|1998-04-20|2002-04-30|Becton Dickinson And Company|Transferset for vials and other medical containers|

US6382442B1|1998-04-20|2002-05-07|Becton Dickinson And Company|Plastic closure for vials and other medical containers|

US5921419A|1998-05-04|1999-07-13|Bracco Research Usa|Universal stopper|

US6692478B1|1998-05-04|2004-02-17|Paradis Joseph R|Swabbable needleless vial access|

CA2262477C|1998-05-16|2008-02-12|Bracco International B.V.|Multiple use universal stopper|

US6117114A|1998-05-07|2000-09-12|Paradis; Joseph R.|Swabbable needleless valve adaptations|

CN100471535C|1998-05-29|2009-03-25|劳伦斯A·林恩|Luer receiver and method for fluid transfer|

US6245044B1|1998-07-17|2001-06-12|Becton, Dickinson And Company|Variable extension combined spinal/epidural needle set and method for its use|

US6358236B1|1998-08-06|2002-03-19|Baxter International Inc.|Device for reconstituting medicaments for injection|

US6089541A|1998-09-10|2000-07-18|Halkey-Roberts Corporation|Valve having a valve body and a deformable stem therein|

US7074216B2|1998-09-15|2006-07-11|Baxter International Inc.|Sliding reconstitution device for a diluent container|

US6022339A|1998-09-15|2000-02-08|Baxter International Inc.|Sliding reconstitution device for a diluent container|

US7425209B2|1998-09-15|2008-09-16|Baxter International Inc.|Sliding reconstitution device for a diluent container|

AR021220A1|1998-09-15|2002-07-03|Baxter Int|CONNECTION DEVICE FOR ESTABLISHING A FLUID COMMUNICATION BETWEEN A FIRST CONTAINER AND A SECOND CONTAINER.|

FR2783808B1|1998-09-24|2000-12-08|Biodome|CONNECTION DEVICE BETWEEN A CONTAINER AND A CONTAINER AND READY-TO-USE ASSEMBLY COMPRISING SUCH A DEVICE|

US6726672B1|1998-09-28|2004-04-27|Icu Medical, Inc.|Intravenous drug access system|

US6113068A|1998-10-05|2000-09-05|Rymed Technologies|Swabbable needleless injection port system having low reflux|

US6364866B1|1999-01-22|2002-04-02|Douglas Furr|Syringe loading aid|

FR2789369B1|1999-02-10|2001-04-27|Biodome|CONNECTION DEVICE BETWEEN A CONTAINER AND A CONTAINER AND READY-TO-USE ASSEMBLY COMPRISING SUCH A DEVICE|

EP1034809A1|1999-02-26|2000-09-13|F. Hoffmann-La Roche Ag|Administering device for medication|

FR2790948B1|1999-03-18|2001-06-22|Sedat|DEVICE FOR BIDIRECTIONAL TRANSFER OF A LIQUID BETWEEN A BOTTLE AND A CAPSULE|

US6099511A|1999-03-19|2000-08-08|Merit Medical Systems, Inc.|Manifold with check valve positioned within manifold body|

US6231552B1|1999-05-04|2001-05-15|Saf-T-Med, Inc.|Threaded latching mechanism|

US6156025A|1999-06-17|2000-12-05|Bracco Research Usa Inc.|Twist valve|

US6706022B1|1999-07-27|2004-03-16|Alaris Medical Systems, Inc.|Needleless medical connector with expandable valve mechanism|

US6348044B1|1999-10-12|2002-02-19|George D. N. Coletti|Method and apparatus for recapping single-use hypodermic needles|

JP4236842B2|1999-10-22|2009-03-11|アンタレス・ファーマ・インコーポレーテッド|Medical syringe and drug loading system used therewith|

US7198618B2|1999-11-04|2007-04-03|Tyco Healthcare Group Lp|Safety shield for medical needles|

FR2800713B1|1999-11-05|2002-01-04|Biodome|CONNECTION DEVICE BETWEEN A CONTAINER AND A CONTAINER AND READY-TO-USE ASSEMBLY COMPRISING SUCH A DEVICE|

US6253804B1|1999-11-05|2001-07-03|Minimed Inc.|Needle safe transfer guard|

US6453956B2|1999-11-05|2002-09-24|Medtronic Minimed, Inc.|Needle safe transfer guard|

US6428505B1|1999-11-19|2002-08-06|Prismedical Corporation|In-line IV drug delivery pack with controllable dilution|

DE19960226C1|1999-12-14|2001-05-10|Fresenius Ag|Connection system, for two or more sterile systems, comprises male and female connectors with threshold breakage points inside the fluid supply system.|

US7799009B2|2000-01-24|2010-09-21|Bracco Diagnostics Inc.|Tabletop drug dispensing vial access adapter|

US6139534A|2000-01-24|2000-10-31|Bracco Diagnostics, Inc.|Vial access adapter|

US6503240B1|2000-01-24|2003-01-07|Brocco Diagnostics, Inc.|Vial access adapter|

US6832994B2|2000-01-24|2004-12-21|Bracco Diagnostics Inc.|Table top drug dispensing vial access adapter|

US6544246B1|2000-01-24|2003-04-08|Bracco Diagnostics, Inc.|Vial access adapter and vial combination|

US6706031B2|2000-02-15|2004-03-16|Comar, Inc.|Needleless access apparatus and system|

AT275914T|2000-02-16|2004-10-15|Haselmeier S A R L|METHOD FOR RECONSTITUTING AN INJECTION LIQUID, AND INJECTION DEVICE FOR CARRYING OUT SUCH A METHOD|

US6530903B2|2000-02-24|2003-03-11|Xiping Wang|Safety syringe|

GB2359754B|2000-03-03|2004-04-28|Nmt Group Plc|Needle sheath|

US6652509B1|2000-04-03|2003-11-25|Abbott Laboratories|Housing capable of connecting a container to a medical device|

JP4372310B2|2000-04-10|2009-11-25|ニプロ株式会社|Adapter for mixed injection|

US6343629B1|2000-06-02|2002-02-05|Carmel Pharma Ab|Coupling device for coupling a vial connector to a drug vial|

US6499617B1|2000-07-17|2002-12-31|Brocco Diagnostics, Inc.|Rotary seal stopper|

JP2002035140A|2000-07-21|2002-02-05|Terumo Corp|Connector|

ES2765665T3|2000-08-02|2020-06-10|Becton Dickinson Co|Pen needle system and safety shield|

CA2422692A1|2000-09-21|2002-03-28|Elan Pharma International Limited|Reconstitution and injection system|

FR2815328B1|2000-10-17|2002-12-20|Biodome|CONNECTION DEVICE BETWEEN A CONTAINER AND A CONTAINER AND READY-TO-USE ASSEMBLY COMPRISING SUCH A DEVICE|

US6769430B1|2000-10-31|2004-08-03|Kimberly-Clark Worldwide, Inc.|Heat and moisture exchanger adaptor for closed suction catheter assembly and system containing the same|

JP2002177392A|2000-11-08|2002-06-25|West Pharmaceutical Services Inc|Safety device of syringe|

US6666852B2|2000-12-04|2003-12-23|Bracco Diagnostics, Inc.|Axially activated vial access adapter|

FR2817566B1|2000-12-04|2003-02-07|Freyssinet Int Stup|INDIVIDUALLY PROTECTED CORD, USE THEREOF IN CONSTRUCTION, AND MANUFACTURING METHOD|

US20020087118A1|2000-12-29|2002-07-04|Duoject Medical Systems Inc.|Pharmaceutical delivery system|

US6558365B2|2001-01-03|2003-05-06|Medimop Medical Projects, Ltd.|Fluid transfer device|

US6474375B2|2001-02-02|2002-11-05|Baxter International Inc.|Reconstitution device and method of use|

WO2002066100A2|2001-02-20|2002-08-29|Medrad, Inc.|Syringes, connectors, and syringe and connector systems for use in fluid delivery systems|

US6656433B2|2001-03-07|2003-12-02|Churchill Medical Systems, Inc.|Vial access device for use with various size drug vials|

US6503244B2|2001-03-07|2003-01-07|Micro Therapeutics, Inc.|High pressure injection system|

US6685692B2|2001-03-08|2004-02-03|Abbott Laboratories|Drug delivery system|

US20020138045A1|2001-03-20|2002-09-26|Moen Michael E.|Quick connect fitting|

CA2440873C|2001-03-27|2010-12-07|Eli Lilly And Company|Kit including side firing syringe needle for preparing a drug in an injection pen cartridge|

US6581593B1|2001-04-03|2003-06-24|Darren A. Rubin|Universal oxygen connector system|

WO2002089900A1|2001-05-07|2002-11-14|Nexell Therapeutics Inc.|Fluid connector devices and methods of use|

JP2002355318A|2001-06-01|2002-12-10|Terumo Corp|Connector with valve body|

EP1264609B1|2001-06-06|2006-01-18|Graziano Azzolini|High-sterility and high-capacity connector for lines for outflow from bottles|

JP2003033441A|2001-07-23|2003-02-04|Terumo Corp|Three-way cock|

US6453949B1|2001-08-08|2002-09-24|Sam Chau|Plug for medical bayonet connectors and drug infusion ports|

US6745998B2|2001-08-10|2004-06-08|Alaris Medical Systems, Inc.|Valved male luer|

DE10142450C1|2001-08-31|2003-06-18|Aventis Behring Gmbh|Device for bringing components together under sterile conditions|

FR2829691B1|2001-09-17|2004-07-09|Sedat|DEVICE FOR BIDIRECTIONAL TRANSFER OF A LIQUID BETWEEN A BOTTLE AND A CARPULE|

US7354422B2|2001-09-26|2008-04-08|B. Braun Melsungen Ag|Spring launched needle safety clip|

JP4817564B2|2001-09-28|2011-11-16|株式会社細川洋行|Needle case and infusion container|

DE10149251B4|2001-10-05|2007-04-19|Sartorius Ag|Device for genetic immunization by introducing active substances into a tissue and method for producing a solution for injection|

US6715520B2|2001-10-11|2004-04-06|Carmel Pharma Ab|Method and assembly for fluid transfer|

US20030073971A1|2001-10-17|2003-04-17|Saker Gordon Mark|Universal connector and method for securing flexible tube assemblies|

CN1332722C|2001-11-14|2007-08-22|株式会社Jms|Three-way stopcock, and liquid transfusion circuit or blood transfusion circuit using the three-way stopcock|

US6802828B2|2001-11-23|2004-10-12|Duoject Medical Systems, Inc.|System for filling and assembling pharmaceutical delivery devices|

US6802490B2|2001-11-29|2004-10-12|Alaris Medical Systems, Inc.|Needle free medical connector with expanded valve mechanism and method of fluid flow control|

AU2002365290B2|2001-11-30|2008-05-01|Novo Nordisk A/S|A safety needle assembly|

EP1453561B1|2001-12-13|2016-08-31|Becton Dickinson and Company|Needle closure system removal device|

DE60210735T2|2001-12-17|2007-03-29|Bristol-Myers Squibb Co.|Transfer device and system with a cap assembly, a container and the transfer device|

US6651956B2|2002-01-31|2003-11-25|Halkey-Roberts Corporation|Slit-type swabable valve|

US6875205B2|2002-02-08|2005-04-05|Alaris Medical Systems, Inc.|Vial adapter having a needle-free valve for use with vial closures of different sizes|

FR2836129B1|2002-02-20|2004-04-02|Biodome|CONNECTION DEVICE BETWEEN A CONTAINER AND A CONTAINER AND READY-TO-USE ASSEMBLY COMPRISING SUCH A DEVICE|

US8562583B2|2002-03-26|2013-10-22|Carmel Pharma Ab|Method and assembly for fluid transfer and drug containment in an infusion system|

US9440046B2|2002-04-04|2016-09-13|Angiodynamics, Inc.|Venous insufficiency treatment method|

US7744581B2|2002-04-08|2010-06-29|Carmel Pharma Ab|Device and method for mixing medical fluids|

US7867215B2|2002-04-17|2011-01-11|Carmel Pharma Ab|Method and device for fluid transfer in an infusion system|

CN100482288C|2002-05-16|2009-04-29|斯科特实验室公司|Drug container entry mechanisms and method|

JP4427965B2|2002-07-02|2010-03-10|ニプロ株式会社|Chemical container with communication means|

SE523001C2|2002-07-09|2004-03-23|Carmel Pharma Ab|Coupling component for transmitting medical substances, comprises connecting mechanism for releasable connection to second coupling component having further channel for creating coupling, where connecting mechanism is thread|

JP4209642B2|2002-07-26|2009-01-14|川澄化学工業株式会社|Needle cover and needle cover with cap and needle with wing with needle cover|

US7326188B1|2002-08-02|2008-02-05|Elcam Medical|Anesthesia manifold and induction valve|

US7083600B2|2002-08-08|2006-08-01|Advanced Medical Sharps, Inc.|Safety needle and shield|

JP2004097253A|2002-09-04|2004-04-02|Nipro Corp|Liquid transfusion device|

US20040073189A1|2002-10-09|2004-04-15|Phil Wyatt|Vial access transfer set|

US7544191B2|2002-10-22|2009-06-09|Baxter International Inc.|Formed, filled, sealed solution container, port and method for establishing flow between the container and an administration set|

US20060155257A1|2002-11-08|2006-07-13|Reynolds David L|Pharmaceutical delivery systems and methods for using same|

US8100879B2|2002-11-18|2012-01-24|Nestec S.A.|Connector device for enteral administration set|

CH696186A5|2002-11-25|2007-02-15|Tecpharma Licensing Ag|Device for securing hypodermic needles.|

CA103134S|2002-11-26|2004-08-11|Nipro Corp|Adapter for transfer of medical solution|

US7086431B2|2002-12-09|2006-08-08|D'antonio Consultants International, Inc.|Injection cartridge filling apparatus|

JP4341239B2|2002-12-19|2009-10-07|ニプロ株式会社|Liquid transfer tool|

US7125396B2|2002-12-30|2006-10-24|Cardinal Health 303, Inc.|Safety catheter system and method|

US7140592B2|2002-12-31|2006-11-28|Cardinal Health 303, Inc.|Self-sealing male Luer connector with biased valve plug|

ES2397833T3|2003-03-05|2013-03-11|Csl Behring Gmbh|Transfer device|

AT375181T|2003-03-06|2007-10-15|Csl Behring Gmbh|TRANSFER DEVICE, ESPECIALLY FOR MEDICAL FLUIDS|

US20040181192A1|2003-03-11|2004-09-16|Cuppy Michael John|Vascular access device and method of using same|

US7470262B2|2003-03-17|2008-12-30|Nipro Corporation|Medical valve|

US7470265B2|2003-03-20|2008-12-30|Nxstage Medical, Inc.|Dual access spike for infusate bags|

US7024968B2|2003-03-26|2006-04-11|Boston Scientific Scimed, Inc.|Luer lock wrench|

US7001369B2|2003-03-27|2006-02-21|Scimed Life Systems, Inc.|Medical device|

US7040598B2|2003-05-14|2006-05-09|Cardinal Health 303, Inc.|Self-sealing male connector|

US6948522B2|2003-06-06|2005-09-27|Baxter International Inc.|Reconstitution device and method of use|

US7520489B2|2003-06-17|2009-04-21|Filtertek Inc.|Fluid handling device and method of making same|

FR2856660A1|2003-06-30|2004-12-31|Biodome|CONNECTION DEVICE BETWEEN A CONTAINER AND A CONTAINER AND READY-TO-USE ASSEMBLY COMPRISING SUCH A DEVICE|

JP3883527B2|2003-07-17|2007-02-21|ニプロ株式会社|Transfer needle|

US7488297B2|2003-07-30|2009-02-10|Patrice Flaherty|Blood collecting devices|

FR2858931B1|2003-08-21|2007-04-13|Becton Dickinson France|DEVICE FOR ORAL ADMINISTRATION OF A MEDICINAL PRODUCT|

US20050082828A1|2003-09-12|2005-04-21|Wicks Jeffrey C.|Releasable connection assembly for joining tubing sections|

SI2664550T1|2003-10-30|2020-03-31|Simplivia Healtcare Ltd.,|Safety Drug Handling Device|

FR2863161B1|2003-12-05|2006-09-01|Map France|CAP FOR SAFETY PACKAGING FOR BOTTLES FOR MEDICAL USE|

US7712637B2|2003-12-11|2010-05-11|Gregory Lambrecht|Wine extraction and preservation device and method|

US20080009822A1|2003-12-18|2008-01-10|Halkey-Roberts Corporation|Needleless access vial|

AU2004317020A1|2003-12-18|2005-09-15|Halkey-Roberts Corporation|Needleless access vial|

US8454573B2|2008-05-06|2013-06-04|Philip Wyatt|Medicament administration apparatus|

US6997916B2|2004-01-02|2006-02-14|Smiths Medical Asd, Inc.|Fluid transfer holder assembly and a method of fluid transfer|

US7530546B2|2004-01-13|2009-05-12|Rymed Technologies, Inc.|Swabbable needle-free injection port valve system with zero fluid displacement|

US6994315B2|2004-01-13|2006-02-07|Rymed Technologies, Inc.|Swabbable needle-free injection port valve system with neutral fluid displacement|

DE102004005435B3|2004-02-04|2005-09-15|Haindl, Hans, Dr.|Medical transfer device|

IL160891D0|2004-03-16|2004-08-31|Auto-mix needle|

US20050209554A1|2004-03-19|2005-09-22|Sergio Landau|Needle-free single-use cartridge and injection system|

CA2561187C|2004-03-26|2013-05-28|Cook Incorporated|Method and apparatus for an improved luer fitting connection|

IL161660D0|2004-04-29|2004-09-27|Medimop Medical Projects Ltd|Liquid drug delivery device|

FR2869795B1|2004-05-07|2006-08-04|Sedat Sa|BIDIRECTIONAL TRANSFER DEVICE|

US20050261637A1|2004-05-21|2005-11-24|Halkey-Roberts Corporation|T-port with swabbable valve|

US20060089594A1|2004-10-26|2006-04-27|Sergio Landau|Needle-free injection device|

US7615041B2|2004-07-29|2009-11-10|Boston Scientific Scimed, Inc.|Vial adaptor|

DE202004012714U1|2004-08-12|2004-11-04|Smiths Medical Deutschland Gmbh|Luer lock connector for medical devices|

CA2578989C|2004-09-03|2014-02-25|Elcam Medical Agricultural Cooperative Association Ltd.|Stopcock|

US7731678B2|2004-10-13|2010-06-08|Hyprotek, Inc.|Syringe devices and methods for mixing and administering medication|

JP4821947B2|2004-10-19|2011-11-24|朝日インテック株式会社|Chemical injection device|

US7771383B2|2004-10-22|2010-08-10|Medegen, Inc.|Fluid control device with valve and methods of use|

US7192423B2|2004-11-17|2007-03-20|Cindy Wong|Dispensing spike assembly with removable indicia bands|

US7241285B1|2004-12-06|2007-07-10|Medical Ventures, Inc.|Medical site connection|

US7645274B2|2004-12-10|2010-01-12|Cardinal Health 303, Inc.|Self-sealing male luer connector with multiple seats|

US7523967B2|2004-12-13|2009-04-28|Alcon, Inc.|Tubing fitting|

US20060135948A1|2004-12-16|2006-06-22|Medtronic Vascular, Inc., A Delaware Corporation|Multi-exchange catheter guide member with improved seal|

DE602006017334D1|2005-02-14|2010-11-18|Medimop Medical Projects Ltd|MEDICAL DEVICE FOR THE RECONSTITUTION OF A LIQUID MEDICAMENT IN SITU IN MEDICAL VACUUM|

US20070060904A1|2005-03-14|2007-03-15|Becton, Dickinson And Company|Filling system and method for syringes with short needles|

US20060253084A1|2005-05-03|2006-11-09|Greg Nordgren|Outdwelling slit valves and assemblies for medical liquid flow through a cannula and related methods|

US7648491B2|2005-05-13|2010-01-19|Bob Rogers|Medical substance transfer system|

US20070088293A1|2005-07-06|2007-04-19|Fangrow Thomas F Jr|Medical connector with closeable male luer|

JP2007024928A|2005-07-12|2007-02-01|Nidec Sankyo Corp|Light beam emitting apparatus and image forming apparatus|

US20080249479A1|2005-08-01|2008-10-09|Medimop Medical Projects Ltd.|Liquid Drug Delivery System|

ES2371557T3|2005-08-11|2012-01-05|Medimop Medical Projects Ltd.|TRANSFER DEVICES OF LIQUID DRUGS FOR A RIGHT PRESSURE ADJUSTMENT TO FAILURE IN MEDICINAL ROADS.|

US7882863B2|2005-10-19|2011-02-08|Cd Solutions, Llc|Apparatus and method for mixing and transferring medications|

US7611502B2|2005-10-20|2009-11-03|Covidien Ag|Connector for enteral fluid delivery set|

DK1957028T3|2005-10-30|2017-09-11|Medimop Medical Projects Ltd|Needleless additive control valve|

US7743799B2|2005-11-07|2010-06-29|Industrie Borta S.p.A.|Vented safe handling vial adapter|

DE102005055326A1|2005-11-11|2007-05-16|Storz Karl Gmbh & Co Kg|Connector tube fitting for a medical suction or flushing assembly has outer arrow-shaped profile|

GB0523638D0|2005-11-21|2005-12-28|Cambridge Biostability Ltd|Pharmaceutical device for the administration of substances to patients|

JP2007143813A|2005-11-28|2007-06-14|Nippon Sherwood Medical Industries Ltd|Medical stopcock|

US20070191767A1|2005-12-16|2007-08-16|Medtronic Vascular, Inc.|Bifurcated Catheter Joints|

US7981101B2|2005-12-30|2011-07-19|Carefusion 303, Inc.|Medical vial adapter with reduced diameter cannula and enlarged vent lumen|

AT447923T|2006-02-16|2009-11-15|Hoffmann La Roche|SYSTEM AND DEVICE FOR REMOVING PHARMACEUTICALS|

JP2007222472A|2006-02-24|2007-09-06|Nipro Corp|Medical agent minute-amount administration appliance set|

WO2007101772A1|2006-03-07|2007-09-13|Novo Nordisk A/S|A drug mixing device|

IL174352D0|2006-03-16|2006-08-20|Medimop Medical Projects Ltd|Medical devices for use with carpules|

JP4769103B2|2006-03-17|2011-09-07|日本シャーウッド株式会社|connector|

FR2898812B1|2006-03-24|2008-06-13|Technoflex Sa|LUER CONNECTOR, MEDICAL CONNECTOR AND TRANSFER SET COMPRISING SUCH A CONNECTOR|

JP4775638B2|2006-03-31|2011-09-21|株式会社ジェイ・エム・エス|Communication member, medical container using the same, and infusion dispensing device set|

US7547300B2|2006-04-12|2009-06-16|Icu Medical, Inc.|Vial adaptor for regulating pressure|

JP4820703B2|2006-04-28|2011-11-24|日本シャーウッド株式会社|Liquid infusion tool|

JP4871019B2|2006-05-15|2012-02-08|日本コヴィディエン株式会社|Liquid infusion tool|

ES2570953T3|2006-05-25|2016-05-23|Bayer Healthcare Llc|Assembly procedure of a reconstitution device|

CN101466344B|2006-06-19|2012-06-06|尼普洛株式会社|Liquid medicine preparation kit|

JP2008005974A|2006-06-28|2008-01-17|Nippon Sherwood Medical Industries Ltd|Lure fixing, fitting and connecting structure|

AT465710T|2006-07-21|2010-05-15|Polimoon Medical Packaging As|CONNECTING DEVICE AND STERILE MIXING PROCESS|

US7670326B2|2006-09-25|2010-03-02|Teva Medical Ltd..|Syringe adapter element in drug mixing system|

US8167863B2|2006-10-16|2012-05-01|Carefusion 303, Inc.|Vented vial adapter with filter for aerosol retention|

EP2086623B1|2006-10-25|2011-04-27|ICU Medical, Inc.|Medical connector|

WO2008067506A1|2006-11-30|2008-06-05|Medi-Physics, Inc.|Dual-lumen needle|

WO2008067511A1|2006-11-30|2008-06-05|Medi-Physics, Inc.|Dual-lumen needle with an elongate notch opening|

US7758082B2|2006-12-05|2010-07-20|Nxstage Medical, Inc.|Fluid line connector safety device|

US8002756B2|2006-12-08|2011-08-23|Becton, Dickinson And Company|Method and apparatus for delivering a therapeutic substance through an injection port|

US7900659B2|2006-12-19|2011-03-08|Carefusion 303, Inc.|Pressure equalizing device for vial access|

GB2446778A|2007-02-01|2008-08-27|Pa Knowledge Ltd|Syringe adaptor|

US7883499B2|2007-03-09|2011-02-08|Icu Medical, Inc.|Vial adaptors and vials for regulating pressure|

GB0705782D0|2007-03-26|2007-05-02|Novartis Ag|Vial assemblies|

IL182605D0|2007-04-17|2007-07-24|Medimop Medical Projects Ltd|Fluid control device with manually depressed actuator|

CA2684745C|2007-04-23|2016-06-28|Plastmed Ltd.|Method and apparatus for contamination-free transfer of a hazardous drug|

IL182922D0|2007-05-02|2007-09-20|Medimop Medical Projects Ltd|Automatic liquid drug reconstitution apparatus|

US20080306439A1|2007-06-08|2008-12-11|Nelson M Bud|Devices for mixing and applying a fluid composition|

US8657803B2|2007-06-13|2014-02-25|Carmel Pharma Ab|Device for providing fluid to a receptacle|

US8241265B2|2007-08-01|2012-08-14|Hospira, Inc.|Medicament admixing system|

CA2704933A1|2007-08-21|2009-02-26|Yukon Medical, Llc|Vial access and injection system|

EP2190401B1|2007-08-30|2015-05-20|Carmel Pharma AB|Device, sealing member and fluid container|

US8287513B2|2007-09-11|2012-10-16|Carmel Pharma Ab|Piercing member protection device|

US20110276007A1|2007-09-18|2011-11-10|Igor Denenburg|Safety needle device|

WO2009038860A2|2007-09-18|2009-03-26|Medeq Llc|Medicament mixing and injection apparatus|

IL186290D0|2007-09-25|2008-01-20|Medimop Medical Projects Ltd|Liquid drug delivery devices for use with syringe having widened distal tip|

WO2009060419A2|2007-11-08|2009-05-14|Elcam Medical A.C.A..L. Ltd|Vial adaptor and manufacturing method therfor|

DE102007061346A1|2007-12-17|2009-06-18|Bayer Schering Pharma Aktiengesellschaft|Spike with two thorns|

US9039673B2|2008-01-09|2015-05-26|Novartis Ag|Unitary withdrawal spike unit suitable for factory fitting|

US8287496B2|2008-01-17|2012-10-16|Custom Medical Applications, Inc.|Flow elements for use with flexible spinal needles, needle assemblies and methods therefor|

IL188975D0|2008-01-23|2008-11-03|Medimop Medical Projects Ltd|Fluid control device with stopper|

FR2927533B1|2008-02-18|2011-02-11|P2A Medical|SECURE TRANSFER CAP|

EP2254542B1|2008-02-18|2012-07-04|ICU Medical, Inc.|Vial adaptor|

DE102008002800A1|2008-03-10|2009-09-24|Süddeutsche Feinmechanik GmbH|mixing device|

JP5685522B2|2008-04-01|2015-03-18|ユーコン・メディカル，リミテッド・ライアビリティ・カンパニー|Duplex container fluid transfer device|

US20090267011A1|2008-04-23|2009-10-29|Jason Hatton|Dispensing valve assembly|

FR2931363B1|2008-05-23|2010-06-25|Vygon|CONNECTOR FOR LIQUID CIRCUIT, IN PARTICULAR FOR MEDICAL USE AND USE OF SUCH A CONNECTOR|

US8075550B2|2008-07-01|2011-12-13|Carmel Pharma Ab|Piercing member protection device|

US7967785B2|2008-07-14|2011-06-28|Nipro Healthcare Systems, Llc|Insulin reservoir detection via magnetic switching|

EP2331043A4|2008-08-22|2014-11-19|Circle Biolog Inc|Fluid management devices and methods|

US8480645B1|2008-08-22|2013-07-09|Sambhu N. Choudhury|Multi-dose device for insertion into a vial and method of using the same|

WO2010022870A1|2008-08-30|2010-03-04|Sanofi-Aventis Deutschland Gmbh|Cartridge and needle system therefor|

US8523837B2|2008-10-14|2013-09-03|Mead Johnson Nutrition Company|Nutritive substance delivery container|

US7762524B2|2008-10-20|2010-07-27|Baxter International Inc.|Barrier assembly for use with needleless connector|

EP2355770A1|2008-11-12|2011-08-17|British Columbia Cancer Agency Branch|Vial handling and injection safety systems and connectors|

EP2351548B1|2008-11-21|2016-01-27|Terumo Kabushiki Kaisha|Connector|

CN102223866B|2008-11-25|2014-07-02|株式会社Jms|Connector|

US8556879B2|2008-11-25|2013-10-15|Jms Co., Ltd.|Connector|

US20100160889A1|2008-12-22|2010-06-24|Baxter International Inc.|Vial access spike assembly|

US8512309B2|2009-01-15|2013-08-20|Teva Medical Ltd.|Vial adapter element|

US8123736B2|2009-02-10|2012-02-28|Kraushaar Timothy Y|Cap adapters for medicament vial and associated methods|

US8012132B2|2009-02-24|2011-09-06|Becton, Dickinson And Company|Luer-snap connection and luer-snap syringe|

US8864725B2|2009-03-17|2014-10-21|Baxter Corporation Englewood|Hazardous drug handling system, apparatus and method|

US8182452B2|2009-04-06|2012-05-22|Carefusion 303, Inc.|Closed male luer device for use with needleless access devices|

WO2010120953A2|2009-04-14|2010-10-21|Yukon Medical, Llc|Fluid transfer device|

US7963939B2|2009-04-24|2011-06-21|Thomas Chun|Syringe having extended blending path|

DE202009011019U1|2009-07-01|2010-12-02|Süddeutsche Feinmechanik GmbH|Arrangement for removing a medium from a vial|

JP5333850B2|2009-07-15|2013-11-06|ニプロ株式会社|Connecting device|

US9149624B2|2009-09-02|2015-10-06|Carefusion 303, Inc.|Disinfecting male luer connector caps|

IL201323D0|2009-10-01|2010-05-31|Medimop Medical Projects Ltd|Fluid transfer device for assembling a vial with pre-attached female connector|

AU2010310457B2|2009-10-23|2015-07-02|Amgen Inc.|Vial adapter and system|

IL202069D0|2009-11-12|2010-06-16|Medimop Medical Projects Ltd|Fluid transfer device with sealing arrangement|

IL202070D0|2009-11-12|2010-06-16|Medimop Medical Projects Ltd|Inline liquid drug medical device|

US8480646B2|2009-11-20|2013-07-09|Carmel Pharma Ab|Medical device connector|

US8597232B2|2009-12-23|2013-12-03|Medimop Medical Projects, Ltd.|Medical apparatus and single use kit including linear flow control device for use therewith for reconstitution and administration of liquid drug dosage|

MX2012008190A|2010-01-15|2012-08-03|Bayer Healthcare Llc|Device.|

WO2011101651A1|2010-01-19|2011-08-25|Cambridge Enterprise Limited|Apparatus and methods|

EP2512399B1|2010-02-24|2015-04-08|Medimop Medical Projects Ltd.|Fluid transfer assembly with venting arrangement|

EP2545950A4|2010-03-10|2014-05-07|Terumo Corp|Injection needle assembly and drug injection apparatus|

US8702674B2|2010-04-27|2014-04-22|Crisi Medical Systems, Inc.|Medication and identification information transfer apparatus|

EP2589402B1|2010-06-30|2018-07-25|Nipro Corporation|Spraying device|

US8721627B2|2010-07-22|2014-05-13|Carefusion 303, Inc.|Needleless valve infection prevention and pre-opening device|

RS56017B1|2010-08-25|2017-09-29|Baxalta GmbH|Assembly to facilitate user reconstitution|

US20120078214A1|2010-09-28|2012-03-29|Tyco Healthcare Group Lp|Vial transfer needle assembly|

IL209290D0|2010-11-14|2011-01-31|Medimop Medical Projects Ltd|Inline liquid drug medical device having rotary flow control member|

EP2462913A1|2010-12-10|2012-06-13|Fresenius Medical Care Deutschland GmbH|Insert and vial for the infusion of liquids|

US20120265163A1|2011-04-14|2012-10-18|Marc Bunjiun Cheng|Coupling system to transfer material between containers|

IL212420D0|2011-04-17|2011-06-30|Medimop Medical Projects Ltd|Liquid drug transfer assembly|

CN104135986A|2012-02-29|2014-11-05|赛诺菲-安万特德国有限公司|Extraction device for a single extraction of a medicament from a container|

IN2014DN06788A|2012-03-05|2015-05-22|Becton Dickinson Co|

IL221635D0|2012-08-26|2012-12-31|Medimop Medical Projects Ltd|Drug vial mixing and transfer device for use with iv bag and drug vial|

JP6113859B2|2012-11-30|2017-04-12|ベクトンディキンソンアンドカンパニーリミテッド|Infusion adapter for drug delivery assembly|IL201323D0|2009-10-01|2010-05-31|Medimop Medical Projects Ltd|Fluid transfer device for assembling a vial with pre-attached female connector|

IL202070D0|2009-11-12|2010-06-16|Medimop Medical Projects Ltd|Inline liquid drug medical device|

IL209290D0|2010-11-14|2011-01-31|Medimop Medical Projects Ltd|Inline liquid drug medical device having rotary flow control member|

IL215699D0|2011-10-11|2011-12-29|Medimop Medical Projects Ltd|Liquid drug reconstitution assemblage for use with iv bag and drug vial|

IL219065D0|2012-04-05|2012-07-31|Medimop Medical Projects Ltd|Fluid transfer device with manual operated cartridge release arrangement|

IL221634D0|2012-08-26|2012-12-31|Medimop Medical Projects Ltd|Universal drug vial adapter|

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EP2872100B1|2012-09-13|2017-03-29|Medimop Medical Projects Ltd|Telescopic female drug vial adapter|

US20140257204A1|2013-03-05|2014-09-11|Stuart Robert Lessin|Apparatus for reconstituting and dispensing drugs for topical application|

IL225734D0|2013-04-14|2013-09-30|Medimop Medical Projects Ltd|Ready-to-use drug vial assemblages including drug vial and drug vial closure having fluid transfer member, and drug vial closure therefor|

JP6199483B2|2013-05-10|2017-09-20|メディモップ・メディカル・プロジェクツ・リミテッド|Medical device comprising a vial adapter having an in-line dry drug module|

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JP6700194B2|2014-04-16|2020-05-27|ベクトンディキンソンアンドカンパニーリミテッド|Fluid transfer device|

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KR101620090B1|2015-04-20|2016-05-12|주식회사 티젤바이오|Kit for drug delivery, Apparatus for preparing drug delivery system, and A preparation method of drug delivery system|

US10357429B2|2015-07-16|2019-07-23|West Pharma. Services IL, Ltd.|Liquid drug transfer devices for secure telescopic snap fit on injection vials|

WO2017090042A1|2015-11-25|2017-06-01|Medimop Medical Projects Ltd|Dual vial adapter assemblage including drug vial adapter with self-sealing access valve|

IL245803D0|2016-05-24|2016-08-31|West Pharma Services Il Ltd|Dual vial adapter assemblages including vented drug vial adapter and vented liquid vial adapter|

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IL247376D0|2016-08-21|2016-12-29|Medimop Medical Projects Ltd|Syringe assembly|

US10842983B2|2016-10-06|2020-11-24|Becton, Dickinson And Company|Syringe with enteral connection feature|

IL249408D0|2016-12-06|2017-03-30|Medimop Medical Projects Ltd|Liquid transfer device for use with infusion liquid container and pincers-like hand tool for use therewith for releasing intact drug vial therefrom|

IL251458D0|2017-03-29|2017-06-29|Medimop Medical Projects Ltd|User actuated liquid drug transfer devices for use in ready-to-useliquid drug transfer assemblages|

US11147956B2|2018-06-21|2021-10-19|Becton, Dickinson And Company|Enteral syringe with vented collar|

JP1630477S|2018-07-06|2019-05-07|

JP1648075S|2019-01-17|2019-12-16|

法律状态:
2018-12-18| B06F| Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]|

2019-08-27| B06U| Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]|

2020-03-24| B06A| Patent application procedure suspended [chapter 6.1 patent gazette]|

2020-08-04| B09A| Decision: intention to grant [chapter 9.1 patent gazette]|

2020-12-08| B16A| Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]|Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 27/10/2011, OBSERVADAS AS CONDICOES LEGAIS. |

优先权:

申请号 | 申请日 | 专利标题

IL209290|2010-11-14|

IL20929010A|IL209290D0|2010-11-14|2010-11-14|Inline liquid drug medical device having rotary flow control member|

PCT/IL2011/000829|WO2012063230A1|2010-11-14|2011-10-27|Inline liquid drug medical device having rotary flow control member|

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